- Rod Hallett
- Roddy Swinford
- Roger Griffiths
- Rogue
- Rogue Males
- Roly Botha
- Romania
- Roots
- Rosa Cadenas
- Rosa Cadenas/Appearances
- Rosalene Hide
- Rosemary Davies
- Rosie Cranham
- Rosie Jones
- Rosie Kemper
- Rosie Marcel
- Rosie Sattar
- Ross West
- Rox Adams
- Roxanna MacMillan
- Roxy Bird
- Roy Ellisson
- Roy Hills
- Royal Wiltshire
- Ruby Spark
- Rue d'Bianchi
- Rules of Attraction
- Runaway
- Running
- Running Out
- Running Out of Kisses
- Running on Empty
- Running on Empty (Casualty)
- Running the Gauntlet
- Russ Faber
- Russ Golden
- Russell Boulter
- Russian Endings
- Ruth Cooper
- Ruth Winters
- Ruth Winters/Relationships
- Ryan Firth
- Ryan Firth/Appearances
- Ryan Johnson
- Ryan Owen
- Sacha Levy
- Sacha Levy/Gallery
- Sacharissa Claxton
- Sacrifice
- Saeed Khan
- Sah Brockner
- Sah Brockner/Appearances
- Sahira Shah
- Said Guessous
- Sally Abbott
- Sally Hodge
- Salt and Sugar
- Salvation
- Sam
- Sam Bateman
- Sam Colloby
- Sam Grey
- Sam Henderson
- Sam Kennedy
- Sam Newton
- Sam Nicholls
- Sam Strachan
- Samantha Kellman
- Same Old, Same Old
- Sammy Malone
- Sammy T Dobson
- Sanctuary
- Sandra's Choice
- Sandra Mute
- Sandra Nicholl
- Sandy Harper
- Sanosi Jemal
- Sanosi Jemal's father
- Sanosi Jemal's mother
- Sara Stewart
- Sarah Jayne Dunn
- Sarah Manners
- Sarah Seggari
- Saturday Night Fever
- Saturday Night Fever (series 22)
- Saturday Night Fever (series 26)
- Say It with Flowers
- Say Say My Playmate
- Say a Little Prayer
- Scapegoat
- Scarlett Conway
- Scars
- Scars and Nightmares
- Scent of the Roses
- Schoolboy Crush
- Scott "Rocker" Rosher
- Scott Ellisson
- Scott Hedges
- Scott Hedges' father
- Scott Hedges' sister
- Scotty (bombing victim)
- Screwdriver
- Sean Anderson
- Sean Glynn
- Sean Maddox
- Search for the Hero
- Season of Goodwill
- Seasons in the Sun
- Sebastian Dunn
- Sebastian Grayling
- Second Best
- Second Chance
- Second Chances
- Second Coming
- Second Life
- Secrets
- Secrets That We Keep
- Secrets You Keep
- Secrets and Lies
- Secrets and Lies (Holby City)
- Secrets and Lies (series 20)
- Secrets and Lies (series 25)
- Secrets and Lies (series 27)
- See You on the Ice
- Seeing Other People
- Seeing in the Dark
- Seeing the Light
- Seeking Heat
- Seize the Day
- Seize the Night
- Selbridge Ambulance Service
- Selena Donovan
- Self Control
- Send No Flowers
- Separate Lives
- Separation
- Serena Campbell
- Serenity
- Sergeant Taylor
- Series 10 (Casualty)
- Series 10 (Holby City)
- Series 11 (Casualty)
- Series 11 (Holby City)
- Series 12 (Casualty)
- Series 12 (Holby City)
- Series 13 (Casualty)
- Series 13 (Holby City)
- Series 14 (Casualty)
- Series 14 (Holby City)
- Series 15 (Casualty)
- Series 15 (Holby City)
- Series 16 (Casualty)
- Series 16 (Holby City)
- Series 17 (Casualty)
- Series 17 (Holby City)
- Series 18 (Casualty)
- Series 18 (Holby City)
- Series 19 (Casualty)
- Series 19 (Holby City)
- Series 1 (Casualty)
- Series 1 (HolbyBlue)
- Series 1 (Holby City)
- Series 20 (Casualty)
- Series 20 (Holby City)
- Series 21 (Casualty)
- Series 21 (Holby City)
- Series 22 (Casualty)
- Series 22 (Holby City)
- Series 23 (Casualty)
- Series 23 (Holby City)
- Series 24
- Series 25
- Series 26
- Series 27
- Series 28
- Series 29
- Series 2 (Casualty)
- Series 2 (HolbyBlue)
- Series 2 (Holby City)
- Series 30
- Series 31
- Series 32
- Series 33
- Series 34
- Series 35
- Series 36
- Series 37
- Series 3 (Casualty)
- Series 3 (Holby City)
- Series 4 (Casualty)
- Series 4 (Holby City)
- Series 5 (Casualty)
- Series 5 (Holby City)
- Series 6 (Casualty)
- Series 6 (Holby City)
- Series 7 (Casualty)
- Series 7 (Holby City)
- Series 8 (Casualty)
- Series 8 (Holby City)
- Series 9 (Casualty)
- Series 9 (Holby City)
- Severed
- Sex and Death
- Seán Gleeson
- Shades of Love
- Shadow of a Doubt - Part One
- Shadow of a Doubt - Part Two
- Shaheen Jafargholi
- Shai Anderton
- Shalisha James-Davis
- Shame (Casualty)
- Shame (Holby City)
- Shame the Devil
- Shame the Devil (Breaking Point)
- Shanti Gudgeon
- Shared house
- Sharice Brookes
- Sharlene Whyte
- Sharon Duce
- Sharon Gless
- Shaun Blackstock
- Shaun Thomas
- She's Electric
- She's My Baby
- She Loved the Rain
- Sheila (cat)
- Sheila Asike
- Sheila Bobbins
- Shelle Jones
- Shields
- Shifts
- Shirley Franklin
- Shock to the Heart
- Shock to the System
- Shockwaves
- Shona Collins
- Shona Wark
- Short Cuts
- Short Fuses
- Short Story 1
- Short Story 2
- Shot in the Dark
- Should Auld Acquaintance Be Forgot
- Side Effects
- Signed, Sealed, Delivered
- Silence Speaks
- Silent All These Years
- Silent Night
- Silent Night (series 21)
- Silent Night (series 7)
- Silent Ties
- Silverton
- Simon Eastman
- Simon Feathering
- Simon Harper
- Simon Kaminski
- Simon MacCorkindale
- Simon Shaughnessy
- Simon Tanner
- Singh Pharmacy & Stores
- Sink or Swim
- Sinners and Saints
- Sins of Omission
- Sins of Our Fathers
- Sins of the Father
- Sins of the Father (Holby City)
- Sins of the Fathers
- Sins of the Mother
- Siobhan Daley
- Siobhan McKenzie
- Siobhan McKenzie/Appearances
- Sirens
- Sixteen Candles
- Sixty Minutes
- Siân Reeves
- Skin Deep
- Skin Deep (series 20)
- Skin Deep (series 37)
- Skin and Blister
- Skipping a Beat
- Skylar Bryce
- Sleep Well
- Sleeping With the Enemy
- Sliding Doors
- Slipping Under
- Small Disappointments
- Smoke Without Fire
- Smoke and Mirrors
- Smoke and Mirrors (series 11)
- Smoke and Mirrors (series 19)
- Smoke and Mirrors (series 27)
- Smoke and Mirrors (series 6)
- Snake in the Grass
- Snakes and Ladders (series 18)
- Snakes and Ladders (series 3)
- Snezana Lalovic
- Snow Queens
- Snowball
- Sofia Constantin
- Sofie Barker
- Soft Centered
- Solomon's Song
- Solomon Cole
- Some Comfort, No Joy, and a Bit Too Much Love
- Somebody to Love
- Someone's Lucky Night
- Someone to Look After Me
- Someone to Watch Over Me
- Someone to Watch Over Me (Holby City)
- Someone to Watch Over Me (series 16)
- Someone to Watch Over Me (series 23)
- Somerview
- Something's Gotta Give
- Something Borrowed, Something Blue
- Something From the Heart
- Something We Can Do
- Something in the Air
- Something to Hide
- Something to Live For
- Somewhere Between Silences
- Somewhere Between Silences - Part One
- Somewhere Between Silences - Part Two
- Somnang Lim
- Song of Self - Part One
- Song of Self - Part Two
- Sons and Lovers
- Sophia Collier
- Sophia Di Martino
- Sophie Austin
- Sorcha Cusack
- Souad Faress
- Speak True
- Special episodes
- Spence's Choice - Part One
- Spence's Choice - Part Two
- Spencer
- Spin
- Spiral Staircases
- Spiteful God
- Springflower
- Square One
- Squeeze the Pips
- St. Simon's House
- St Eugene's Hospital
- St James' Hospital
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