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Mark Williams is a former nurse and CEO at Holby City Hospital. Mark is the half brother of Chrissie Williams. He first appeared on 15 February 2005 as a staff nurse and departed on 25 January 2011 as a CEO. Mark is portrayed by Robert Powell .

Mark's a carefree rogue, a wild child of the 60's. He was a rolling stone, always looking for an excuse to go on the run, until he reconnected with his daughter Chrissie. Mark often feels torn between being a good father and doing the best job. He was always a man of the people so landing the CEO job has given Mark the opportunity to make a difference. But can he reconcile his principles with his new senior position?