"Twist of the Knife" is the 873rd episode of Holby City and the 34th episode of the 19th Series. This is the first episode that Simon Harper appears in the credits as executive producer, taking over as series producer is Kate Hall.


After discovering Mr T's lack of faith in her professional ability, Mo is prepared to forgive. However, when an unimaginable event unfolds on Darwin, Mo's fight for survival has far-reaching consequences.

Aware that Matteo has his eye on her, Nina is determined to be the consummate professional on her first day as locum on AAU. But when she and Matteo receive devastating news, is Nina fully prepared for a future at Holby?

When Essie helps Dominic recruit a team for the Holby half marathon, Raf makes a startling discovery.