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Vanessa Lytton is a former Chief Executive Officer (CEO) of Holby City Hospital.

Time at Holby City Hospital

Vanessa arrives in Holby as the new Chief Executive Officer of Holby City Hospital, replacing former CEO Jayne Grayson. She is recruited by Director of Surgery Michael Spence, having previously worked with him when she was a nurse. Vanessa's first act as CEO is to approve funding for a robotics scheme run by cardiothoracic consultant Connie Beauchamp. Soon thereafter, she suspends Connie, general surgical consultant Ric Griffin and ward sister Faye Byrne over the death of Archie Morton, Faye's disabled son, unaware that the true culprit in his death is nurse Lauren Minster. Vanessa goes on to appoint former surgical registrar Thandie Abebe-Griffin as a locum on the cardiothoracic ward, causing tension with consultant Elliot Hope, who Thandie once accused of racial discrimination.

Vanessa Left on 30 March. She left after making a show of Michael in the Board Room. Michael decides that she should leave after Mark says that he has written his resgination and that Maria should be given compensation for her back injury.

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